> Pathway Inhibitors>Enzyme Inhibitors>DO53

Enzyme Inhibitors

DO53 View larger

DO53

AOB8065

CAS: 1848233-59-9

 

Chemical Name: 3-Phenyl-4-[[4-[4-(trifluoromethoxy)phenyl]-1H-1,2,3-triazol-1-yl]carbonyl]-1-piperazinecarboxylic acid 1,1-dimethylethyl ester

More details

Molarity Calculation Cart®

HOW TO ORDER

$37.50

$37.50 per mg

Add to my wishlist

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $16.88 Total: $1,687.50
150 $19.50 Total: $975.00
125 $22.88 Total: $571.88
110 $27.00 Total: $270.00
15 $31.88 Total: $159.38

Data sheet

Molecular FormulaC25H26F3N5O4
Molecular Weight517.51
CAS Numbers1848233-59-9
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
IUPAC/Chemical Name3-Phenyl-4-[[4-[4-(trifluoromethoxy)phenyl]-1H-1,2,3-triazol-1-yl]carbonyl]-1-piperazinecarboxylic acid 1,1-dimethylethyl ester
InChl KeyMCQNBNJCBIKELG-UHFFFAOYSA-N
InChl CodeInChI=1S/C25H26F3N5O4/c1-24(2,3)37-23(35)31-13-14-32(21(16-31)18-7-5-4-6-8-18)22(34)33-15-20(29-30-33)17-9-11-19(12-10-17)36-25(26,27)28/h4-12,15,21H,13-14,16H2,1-3H3
SMILES CodeO=C(N1CC(C2=CC=CC=C2)N(C(N3N=NC(C4=CC=C(OC(F)(F)F)C=C4)=C3)=O)CC1)OC(C)(C)C
References1) Deng H, Kooijman S, van den Nieuwendijk AM, Ogasawara D, van der Wel T, van Dalen F, Baggelaar MP, Janssen FJ, van den Berg RJ, den Dulk H, Cravatt BF, Overkleeft HS, Rensen PC, van der Stelt M. Triazole Ureas Act as Diacylglycerol Lipase Inhibitors and Prevent Fasting-Induced Refeeding. J Med Chem. 2017 Jan 12;60(1):428-440. doi: 10.1021/acs.jmedchem.6b01482. Epub 2016 Dec 19. PubMed PMID: 27992221.

2) Witter K, Matulová P, Mísek I. Three-dimensional reconstruction studies and morphometric analysis of rudimental tooth primordia in the upper incisor region of the sheep (Ovis aries, Ruminantia). Arch Oral Biol. 2003 Jan;48(1):15-24. PubMed PMID: 12615137.

More info

Negative control for DO34, not inhibiting DAGL