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GSK3368715 (EPZ019997)
AOB11277
CAS: 1629013-22-4
Chemical Name: EPZ019997; N1-((3-(4,4-Bis(ethoxymethyl)cyclohexyl)-1H-pyrazol-4-yl)methyl)-N1,N2-dimethylethane-1,2-diamine
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $17.55 | Total: $1,755.00 |
| 1 | 50 | $20.28 | Total: $1,014.00 |
| 1 | 25 | $23.79 | Total: $594.75 |
| 1 | 10 | $28.08 | Total: $280.80 |
| 1 | 5 | $33.15 | Total: $165.75 |
Data sheet
| Molecular Formula | C20H38N4O2 |
| Molecular Weight | 366.55 |
| CAS Numbers | 1629013-22-4 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | GSK3368715; GSK-3368715; GSK 3368715; EPZ019997; EPZ-019997; EPZ 019997; GSK3368715 free base |
| IUPAC/Chemical Name | N1-((3-(4,4-bis(ethoxymethyl)cyclohexyl)-1H-pyrazol-4-yl)methyl)-N1,N2-dimethylethane-1,2-diamine |
| InChl Key | SPEGERVLTUWZPA-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C20H38N4O2/c1-5-25-15-20(16-26-6-2)9-7-17(8-10-20)19-18(13-22-23-19)14-24(4)12-11-21-3/h13,17,21H,5-12,14-16H2,1-4H3,(H,22,23) |
| SMILES Code | CNCCN(CC1=CNN=C1C2CCC(COCC)(COCC)CC2)C |
| References | Srour N, Mersaoui SY, Richard S. M-TAP Dance: Targeting PRMT1 and PRMT5 Family Members to Push Cancer Cells Over the Edge. Cancer Cell. 2019 Jul 8;36(1):3-5. doi: 10.1016/j.ccell.2019.06.004. PubMed PMID: 31287990. |
More info
A first-in-class, orally active, potent and selective, SAM-Noncompetive inhibitor of Type I Protein Arginine Methyltransferases (PRMTs) with IC50 in lower nM