Enzyme Inhibitors

Y15 View larger

Y15

AOB9830

CAS: 4506-66-5

 

Chemical Name: 1,2,4,5-Benzenetetramine tetrahydrochloride

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$15.00

$15.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $6.75 Total: $675.00
150 $7.80 Total: $390.00
125 $9.15 Total: $228.75
110 $10.80 Total: $108.00
15 $12.75 Total: $63.75

Data sheet

Molecular FormulaC6H14Cl4N4
Molecular Weight284.01
CAS Numbers4506-66-5 (HCl)
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymY15 hydrochloride; Y15 tetrahydrochloride; Y 15; Y-15. FAK Inhibitor 14.
IUPAC/Chemical Name1,2,4,5-benzenetetramine tetrahydrochloride
InChl KeyBZDGCIJWPWHAOF-UHFFFAOYSA-N
InChl CodeInChI=1S/C6H10N4.4ClH/c7-3-1-4(8)6(10)2-5(3)9;;;;/h1-2H,7-10H2;4*1H
SMILES CodeNC1=CC(N)=C(N)C=C1N.[H]Cl.[H]Cl.[H]Cl.[H]Cl
References1) Golubovskaya V, et al. Down-regulation of ALDH1A3, CD44 or MDR1 sensitizes resistant cancer cells to FAK autophosphorylation inhibitor Y15. J Cancer Res Clin Oncol. 2015 Sep;141(9):1613-31. doi: 10.1007/s00432-015-1924-3. PubMed PMID: 25656374.

2) Golubovskaya V, Curtin L, Groman A, Sexton S, Cance WG. In vivo toxicity, metabolism and pharmacokinetic properties of FAK inhibitor 14 or Y15 (1, 2, 4, 5-benzenetetramine tetrahydrochloride). Arch Toxicol. 2015 Jul;89(7):1095-101. doi: 10.1007/s00204-014-1290-y. PubMed PMID: 24915938.

More info

Potent and specific inhibitor of focal adhesion kinase (FAK) autophosphorylation