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AOB8923
CAS: 1462249-75-7
Chemical Name: (E)-1-Pyridin-4-yl-3-[7-(trifluoromethyl)quinolin-2-yl]prop-2-en-1-one
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Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
---|---|---|---|
1 | 100 | $6.75 | Total: $675.00 |
1 | 50 | $7.80 | Total: $390.00 |
1 | 25 | $9.15 | Total: $228.75 |
1 | 10 | $10.80 | Total: $108.00 |
1 | 5 | $12.75 | Total: $63.75 |
Molecular Formula | C18H11F3N2O |
Molecular Weight | 328.29 |
CAS Numbers | 1462249-75-7 |
Storage Condition | 0°C (short term), -20°C (long term), desiccated |
Solubility | DMSO |
Purity | 98% by HPLC |
Synonym | PFK158; PFK 158; PFK158; ACTPFK158. |
IUPAC/Chemical Name | (E)-1-(pyridin-4-yl)-3-(7-(trifluoromethyl)quinolin-2-yl)prop-2-en-1-one |
InChl Key | IAJOMYABKVAZCN-AATRIKPKSA-N |
InChl Code | InChI=1S/C18H11F3N2O/c19-18(20,21)14-3-1-12-2-4-15(23-16(12)11-14)5-6-17(24)13-7-9-22-10-8-13/h1-11H/b6-5+ |
SMILES Code | O=C(C1=CC=NC=C1)/C=C/C2=NC3=CC(C(F)(F)F)=CC=C3C=C2 |
References | 1) Zhang Y, Wang X, Li X, Dong L, Hu X, Nie T, Lu Y, Lu X, Pang J, Li G, Yang X, Li C, You X. Synergistic Effect of Colistin Combined with PFK-158 against Colistin-Resistant Enterobacteriaceae. Antimicrob Agents Chemother. 2019 Jun 24;63(7). pii: e00271-19. doi: 10.1128/AAC.00271-19. Print 2019 Jul. PubMed PMID: 30988150; PubMed Central PMCID: PMC6591609. |
Novel inhibitor of PFKFB3, displaying broad anti-tumor activity