Enzyme Inhibitors

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DCPP

AOB31525

CAS: 41202-77-1

 

Chemical Name: (2,3-Dichlorophenyl)piperazine

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Data sheet

Molecular FormulaC10H12Cl2N2
Molecular Weight231.12
CAS Numbers41202-77-1
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
IUPAC/Chemical Name(2,3-Dichlorophenyl)piperazine
InChl KeyUDQMXYJSNNCRAS-UHFFFAOYSA-N
InChl CodeInChI=1S/C10H12Cl2N2/c11-8-2-1-3-9(10(8)12)14-6-4-13-5-7-14/h1-3,13H,4-7H2
SMILES CodeClC1=C(Cl)C(N2CCNCC2)=CC=C1
References1) Thiago C. et al., Dichlorophenyl piperazines, including a recently-approved atypical antipsychotic, are potent inhibitors of DHCR7, the last enzyme in cholesterol biosynthesis, Toxicol Appl Pharmacol. 2018 Jun 15; 349: 21–28.

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Potent inhibitor of DHCR7, the last enzyme in cholesterol biosynthesis