Enzyme Inhibitors

PKM2 inhibitor 2825-0090 View larger

PKM2 inhibitor 2825-0090

AOB13354

CAS: 313701-92-7

 

Chemical Name: 5-(2,5-Dimethyl-1H-pyrrol-1-yl)-2-hydroxybenzoic acid; 1-(3-Carboxy-4-hydroxy)phenyl-2,5-dimethylpyrrole

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$45.00

$45.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $20.25 Total: $2,025.00
150 $23.40 Total: $1,170.00
125 $27.45 Total: $686.25
110 $32.40 Total: $324.00
15 $38.25 Total: $191.25

Data sheet

Molecular FormulaC13H13NO3
Molecular Weight231.25
CAS Numbers313701-92-7
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymPyruvate Kinase Inhibitor III
IUPAC/Chemical Name5-(2,5-Dimethyl-1H-pyrrol-1-yl)-2-hydroxybenzoic acid; 1-(3-Carboxy-4-hydroxy)phenyl-2,5-dimethylpyrrole
InChl KeyRPNDNUTUEQJRBE-UHFFFAOYSA-N
InChl CodeInChI=1S/2C13H13NO3/c2*1-8-3-4-9(2)14(8)10-5-6-12(15)11(7-10)13(16)17/h2*3-7,15H,1-2H3,(H,16,17)
SMILES CodeO=C(O)C1=CC(N2C(C)=CC=C2C)=CC=C1O.CC3=CC=C(C)N3C4=CC=C(O)C(C(O)=O)=C4
References1) Zhou Y, et al.,. Benserazide is a novel inhibitor targeting PKM2 for melanoma treatment. Int J Cancer. 2019 Oct 25. doi: 10.1002/ijc.32756. [Epub ahead of print] PubMed PMID: 31652354.

2) Zhou Q, Sun Y. MLN4924: additional activities beyond neddylation inhibition. Mol Cell Oncol. 2019 May 22;6(5):e1618174. doi: 10.1080/23723556.2019.1618174. eCollection 2019. PubMed PMID: 31528694; PubMed Central PMCID: PMC6736204.

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