Enzyme Inhibitors

ML136 (AMZ30) View larger

ML136 (AMZ30)

AOB1545

CAS No:1313613-09-0

Chemical Name: AMZ-30; (E)-2-(4-Fluorophenyl)sulfonyl-3-[1-(3-nitrophenyl)sulfonylpyrrol-2-yl]prop-2-enenitrile; ML-136

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$19.00

$19.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $8.55 Total: $855.00
150 $9.88 Total: $494.00
125 $11.59 Total: $289.75
110 $13.68 Total: $136.80
15 $16.15 Total: $80.75

Data sheet

Molecular FormulaC19H12FN3O6S2
Molecular Weight461.44
CAS Numbers1313613-09-0
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymAM-Z30; AM Z30; ML 136; ML-136
IUPAC/Chemical Name(E)-2-(4-fluorophenyl)sulfonyl-3-[1-(3-nitrophenyl)sulfonylpyrrol-2-yl]prop-2-enenitrile
InChl KeyGUCUORSUHTZMBW-YBFXNURJSA-N
InChl CodeInChI=1S/C19H12FN3O6S2/c20-14-6-8-17(9-7-14)30(26,27)19(13-21)11-15-4-2-10-22(15)31(28,29)18-5-1-3-16(12-18)23(24)25/h1-12H/b19-11+
SMILES CodeC1=CC(=CC(=C1)S(=O)(=O)N2C=CC=C2C=C(C#N)S(=O)(=O)C3=CC=C(C=C3)F)[N+](=O)[O-]
References1) . Bachovchin DA, et al. Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. J Med Chem. 2011 Jul 28;54(14):5229-36.

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Potent, selective inhibitor of protein phosphatase methylesterase-1 (PME-1)