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Perifosine
AOB3006
CAS: 157716-52-4
Chemical Name: KRX-0401; NSC-639966; D-21266; NKA17; (1,1-Dimethylpiperidin-1-ium-4-yl) octadecyl phosphate
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $4.95 | Total: $495.00 |
| 1 | 50 | $5.72 | Total: $286.00 |
| 1 | 25 | $6.71 | Total: $167.75 |
| 1 | 10 | $7.92 | Total: $79.20 |
| 1 | 5 | $9.35 | Total: $46.75 |
Data sheet
| Molecular Formula | C25H52NO4P |
| Molecular Weight | 461.66 |
| CAS Numbers | 157716-52-4 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | KRX-0401; KRX 0401; KRX0401; NKA17; NSC639966; NSC 639966; NSC-639966; D 21266; D-21266; Perifosine |
| IUPAC/Chemical Name | 1,1-dimethylpiperidin-1-ium-4-yl octadecyl phosphate. |
| InChl Key | SZFPYBIJACMNJV-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C25H52NO4P/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-24-29-31(27,28)30-25-20-22-26(2,3)23-21-25/h25H,4-24H2,1-3H3 |
| SMILES Code | O=P(OC1CC[N+](C)(C)CC1)([O-])OCCCCCCCCCCCCCCCCCC |
| References | 1) Amantini C, et al., Sorafenib induces cathepsin B-mediated apoptosis of bladder cancer cells by regulating the Akt/PTEN pathway. The Akt inhibitor, perifosine, enhances the sorafenib-induced cytotoxicity against bladder cancer cells. Oncoscience. 2015 Mar 23;2(4):395-409. eCollection 2015. PubMed PMID: 26097873; PubMed Central PMCID: PMC4468325.2) Kim MN, Ro SW, Kim DY, Kim DY, Cho KJ, Park JH, Lim HY, Han KH. Efficacy of perifosine alone and in combination with sorafenib in an HrasG12V plus shp53 transgenic mouse model of hepatocellular carcinoma. Cancer Chemother Pharmacol. 2015 Jun 3. [Epub ahead of print] PubMed PMID: 26037205. |
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