Enzyme Inhibitors

Ascomycin (FK520) View larger

Ascomycin (FK520)

AOB5915

CAS No:104987-12-4

Chemical Name:(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R​,19R,26aS)-8-Ethyl-5,6,8,11,12,13,14,15,16,17,18,1​9,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E​)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-m​ethylethenyl]-14,16-dimethoxy-4,10,12,18-tetrameth​yl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotri​cosine-1,7,20,21(4H,23H)tetrone

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$11.00

$11.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $4.95 Total: $495.00
150 $5.72 Total: $286.00
125 $6.71 Total: $167.75
110 $7.92 Total: $79.20
15 $9.35 Total: $46.75

Data sheet

Molecular FormulaC43H69NO12
Molecular Weight792.01
CAS Numbers104987-12-4
Storage Condition0°C (short term), -20°C (long term), desiccated
Solubility50 mMol in DMSO or Ethanol
Purity98% by HPLC

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Analog of FK 506; binds to FK 506-binding protein 12 (FKBP12) in order to inhibit calcineurin phosphatase activity

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