Array
(
)
1
> Pathway Inhibitors>Enzyme Inhibitors>BMS-986158

Enzyme Inhibitors

CC-671 View larger

BMS-986158

AOB33413

CAS: 1800340-40-2

 

Chemical Name: (S)-2-(3-(1,4-Dimethyl-1H-1,2,3-triazol-5-yl)-5-(phenyl(tetrahydro-2H-pyran-4-yl)methyl)-5H-pyrido[3,2-b]indol-7-yl)propan-2-ol

More details

998 Items

Molarity Calculation Cart®

HOW TO ORDER

$59.00

$59.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $50.15 Total: $250.75
110 $42.48 Total: $424.80
125 $35.99 Total: $899.75
150 $30.68 Total: $1,534.00
1100 $26.55 Total: $2,655.00

Data sheet

Molecular FormulaC30H33N5O2
Molecular Weight495.6
CAS Numbers1800340-40-2
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO 50 mM
Purity98% by HPLC
SynonymBMS-986158; BMS986158
IUPAC/Chemical Name3-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-α,α-dimethyl-5-[(S)-phenyl(tetrahydro-2H-pyran-4-yl)methyl]-5H-pyrido[3,2-b]indole-7-methanol
InChl KeyKGERZPVQIRYWRK-GDLZYMKVSA-N
InChl CodeInChI=1S/C30H33N5O2/c1-19-28(34(4)33-32-19)22-16-26-27(31-18-22)24-11-10-23(30(2,3)36)17-25(24)35(26)29(20-8-6-5-7-9-20)21-12-14-37-15-13-21/h5-11,16-18,21,29,36H,12-15H2,1-4H3/t29-/m1/s1
SMILES CodeCC(O)(C)C(C=C1)=CC2=C1C(N=CC(C3=C(C)N=NN3C)=C4)=C4N2[C@H](C5=CC=CC=C5)C6CCOCC6
References1) Gavai, A.V., Norris, D., Tortolani, D., et al. Abstract 5789: Discovery of clinical candidate BMS-986158, an oral BET inhibitor, for the treatment of cancer. Cancer Res. 78(13 Supplement), 5789-5789 (2018).

More info

Novel potent and selective BET inhibitor