Enzyme Inhibitors

Vildagliptin View larger

Vildagliptin

AOB0437

CAS: 274901-16-5

 

Chemical Name: NVP-LAF237; LAF237; (S)-1-[N-(3-Hydroxy-1-adamantyl)glycyl]pyrrolidine-2-carbonitrile

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$9.00

$9.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $4.05 Total: $405.00
150 $4.68 Total: $234.00
125 $5.49 Total: $137.25
110 $6.48 Total: $64.80
15 $7.65 Total: $38.25

Data sheet

Molecular FormulaC17H25N3O2
Molecular Weight303.4
CAS Numbers274901-16-5
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMF: 20 mg/ml DMSO: 15 mg/ml Ethanol: 15 mg/ml PBS (pH 7.2): 10 mg/ml
Purity98% by HPLC
SynonymLAF237; NVP-LAF237
IUPAC/Chemical Name1-[2-[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2S-pyrrolidinecarbonitrile
InChl KeySYOKIDBDQMKNDQ-QWJLZPNVSA-N
InChl CodeInChI=1S/C17H25N3O2/c18-9-14-2-1-3-20(14)15(21)10-19-16-5-12-4-13(6-16)8-17(22,7-12)11-16/h12-14,19,22H,1-8,10-11H2/t12?,13?,14?,16-,17-
SMILES CodeO=C(CN[C@@]1(CC(C2)C3)CC3C[C@]2(O)C1)N4[C@H](C#N)CCC4
References1) Ikuma, Y., Hochigai, H., Kimura, H., et al. Discovery of 3H-imidazol[4,5-c]quinolin-4(5H)-ones as potent and selective dipeptidyl peptidase IV (DPP-4) inhibitors. Bioorg. Med. Chem. 20(19), 5864-5883 (2012).

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Dipeptidyl peptidase-4 (DPP-4) inhibitor