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FRJ (PTP1B Inhibitor)
AOB6014
CAS: 765317-72-4
Chemical Name: PTP1B-IN-3; Compound 3; 3-(3,5-dibromo-4-hydroxy-benzoyl)-2-ethyl-benzofuran-6-sulfonic acid
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $16.65 | Total: $1,665.00 |
| 1 | 50 | $19.24 | Total: $962.00 |
| 1 | 25 | $22.57 | Total: $564.25 |
| 1 | 10 | $26.64 | Total: $266.40 |
| 1 | 5 | $31.45 | Total: $157.25 |
Data sheet
| Molecular Formula | C26H19Br2N3O7S3 |
| Molecular Weight | 741.5 |
| CAS Numbers | 765317-72-4 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMF: 30 mg/ml DMSO: 30 mg/ml DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml Ethanol: 10 mg/ml |
| Purity | > 95% by HPLC |
| Synonym | Protein Tyrosine Phosphatase 1B Inhibitor; FRJ; PTP1B-IN-2; PTP1B IN 2; PTP1BIN2; PTP1B inhibitor 2; PTP1B-inhibitor-2; NUN17724; NUN-17724; NUN 17724; 1T4J |
| IUPAC/Chemical Name | 3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-[4-[(2-thiazolylamino)sulfonyl]phenyl]-6-benzofuransulfonamide |
| InChl Key | SXKBTDJJEQQEGE-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C26H19Br2N3O7S3/c1-2-21-23(24(32)14-11-19(27)25(33)20(28)12-14)18-8-7-17(13-22(18)38-21)41(36,37)30-15-3-5-16(6-4-15)40(34,35)31-26-29-9-10-39-26/h3-13,30,33H,2H2,1H3,(H,29,31) |
| SMILES Code | O=S(NC1=CC=C(S(NC2=NC=CS2)(=O)=O)C=C1)(C3=CC=C(C(C(C4=CC(Br)=C(O)C(Br)=C4)=O)=C(CC)O5)C5=C3)=O |
| References | 1) Zhang, S., and Zhang, Z.Y. PTP1B as a drug target: recent developments in PTP1B inhibitor discovery. Drug Discov. Today 12(9-10), 373-381 (2007). 2) Tonks, N.K. Protein tyrosine phosphatases - from housekeeping enzymes to master regulators of signal transduction. FEBS J. 280(2), 346-378 (2013). |
More info
Novel specific inhibitor of protein tyrosine phosphatase 1B (PTP1B)