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View larger Sanofi-14H
AOB6382
CAS: 1426214-64-3
Chemical Name: Sgk1-IN-2; N-(4-(3-Amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl)-2,5-dichlorobenzenesulfonamide
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $41.65 | Total: $208.25 |
| 1 | 10 | $35.28 | Total: $352.80 |
| 1 | 25 | $29.89 | Total: $747.25 |
| 1 | 50 | $25.48 | Total: $1,274.00 |
| 1 | 100 | $22.05 | Total: $2,205.00 |
Data sheet
| Molecular Formula | C17H12Cl2N6O2S |
| Molecular Weight | 435.29 |
| CAS Numbers | 1426214-64-3 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | SGK1-IN-2 |
| IUPAC/Chemical Name | N-(4-(3-Amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl)-2,5-dichlorobenzenesulfonamide |
| SMILES Code | O=S(C1=CC(Cl)=CC=C1Cl)(NC2=CC=C(C3=CN=C4C(NN=C4N)=N3)C=C2)=O |
| References | 1) Halland N, et al. Discovery of N-[4-(1H-Pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]-sulfonamides as Highly Active and Selective SGK1 Inhibitors. ACS Med Chem Lett. 2014 Oct 23;6(1):73-8. |
More info
Novel potent inhibitor of SGK1/3, reducing PI3K-Akt inhibitor resistant cell growth, possessing an IC50 of 4 nM for SGK3, 10 nM for SGK1, and 76 nM for S6K1