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AOB3604
CAS: 121263-19-2
Chemical Name: Calphostin C; PKF115-584; PKF115584; UCN-1028C; UCN1028C; (1R)-2-[12-[(2R)-2-(Benzoyloxy)propyl]-3,10-dihydro-4,9-dihydroxy-2,6,7,11-tetramethoxy-3,10-dioxo-1-perylenyl]-1-methylethylcarbonic acid 4-hydroxyphenyl ester
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Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
---|---|---|---|
1 | 100 | $697.50 | Total: $69,750.00 |
1 | 50 | $806.00 | Total: $40,300.00 |
1 | 25 | $945.50 | Total: $23,637.50 |
1 | 10 | $1,116.00 | Total: $11,160.00 |
1 | 5 | $1,317.50 | Total: $6,587.50 |
Molecular Formula | C44H38O14 |
Molecular Weight | 790.8 |
CAS Numbers | 121263-19-2 |
Storage Condition | 0°C (short term), -20°C (long term), desiccated |
Solubility | DMSO |
Purity | 98% by HPLC |
Synonym | Cladochrome E; PKF 115-584; UCN 1028C |
IUPAC/Chemical Name | (1R)-2-[12-[(2R)-2-(benzoyloxy)propyl]-3,10-dihydro-4,9-dihydroxy-2,6,7,11-tetramethoxy-3,10-dioxo-1-perylenyl]-1-methylethyl 4-carbonic acid |
InChl Key | SRJYZPCBWDVSGO-NHCUHLMSSA-N |
InChl Code | InChI=1S/C44H38O14/c1-20(56-43(50)22-10-8-7-9-11-22)16-25-31-32-26(17-21(2)57-44(51)58-24-14-12-23(45)13-15-24)42(55-6)40(49)34-28(47)19-30(53-4)36(38(32)34)35-29(52-3)18-27(46)33(37(31)35)39(48)41(25)54-5/h7-15,18-21,45-47H,16-17H2,1-6H3/t20-,21-/m1 |
SMILES Code | OC1=C(C(C(OC)=C(C[C@@H](C)OC(OC2=CC=C(O)C=C2)=O)C3=C(C(C[C@@H](C)OC(C4=CC=CC=C4)=O)=C5OC)C(C6=C(OC)C=C7O)=C7C5=O)=O)C3=C6C(OC)=C1 |
References | 1) Kobayashi, E., et al. Calphostins (UCN-1028), novel and specific inhibitors of protein kinase C. I. Fermentation, isolation, physico-chemical properties and biological activities. J. Antibiot. (Tokyo) 42(10), 1470-1474 (1989). 2. Bruns, R.F., et al. Inhibition of protein kinase C by calphostin C is light-dependent. Biochem. Biophys. Res. Commun. 176(1), 288-293 (1991). |
Novel antagonist of the tcf/ß-catenin complex on endometrial and endometriotic cells with endometriosis; Potent, selective and photo-dependent inhibitor of protein kinase C