Enzyme Inhibitors

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PKF115-584 (Calphostin C)

AOB3604

CAS: 121263-19-2

 

Chemical Name: Calphostin C; PKF115-584; PKF115584; UCN-1028C; UCN1028C; (1R)-2-[12-[(2R)-2-(Benzoyloxy)propyl]-3,10-dihydro-4,9-dihydroxy-2,6,7,11-tetramethoxy-3,10-dioxo-1-perylenyl]-1-methylethylcarbonic acid 4-hydroxyphenyl ester

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$1,550.00

$1,550.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $697.50 Total: $69,750.00
150 $806.00 Total: $40,300.00
125 $945.50 Total: $23,637.50
110 $1,116.00 Total: $11,160.00
15 $1,317.50 Total: $6,587.50

Data sheet

Molecular FormulaC44H38O14
Molecular Weight790.8
CAS Numbers121263-19-2
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymCladochrome E; PKF 115-584; UCN 1028C
IUPAC/Chemical Name(1R)-2-[12-[(2R)-2-(benzoyloxy)propyl]-3,10-dihydro-4,9-dihydroxy-2,6,7,11-tetramethoxy-3,10-dioxo-1-perylenyl]-1-methylethyl 4-carbonic acid
InChl KeySRJYZPCBWDVSGO-NHCUHLMSSA-N
InChl CodeInChI=1S/C44H38O14/c1-20(56-43(50)22-10-8-7-9-11-22)16-25-31-32-26(17-21(2)57-44(51)58-24-14-12-23(45)13-15-24)42(55-6)40(49)34-28(47)19-30(53-4)36(38(32)34)35-29(52-3)18-27(46)33(37(31)35)39(48)41(25)54-5/h7-15,18-21,45-47H,16-17H2,1-6H3/t20-,21-/m1
SMILES CodeOC1=C(C(C(OC)=C(C[C@@H](C)OC(OC2=CC=C(O)C=C2)=O)C3=C(C(C[C@@H](C)OC(C4=CC=CC=C4)=O)=C5OC)C(C6=C(OC)C=C7O)=C7C5=O)=O)C3=C6C(OC)=C1
References1) Kobayashi, E., et al. Calphostins (UCN-1028), novel and specific inhibitors of protein kinase C. I. Fermentation, isolation, physico-chemical properties and biological activities. J. Antibiot. (Tokyo) 42(10), 1470-1474 (1989).

2. Bruns, R.F., et al. Inhibition of protein kinase C by calphostin C is light-dependent. Biochem. Biophys. Res. Commun. 176(1), 288-293 (1991).

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