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SR-18292
AOB37750
CAS No: 2095432-55-4
Chemical Name: 1-[tert-Butyl-(4-methyl-benzyl)-amino]-3-(1H-indol-4-yloxy)-propan-2-ol
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| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $6.75 | Total: $675.00 |
| 1 | 50 | $7.80 | Total: $390.00 |
| 1 | 25 | $9.15 | Total: $228.75 |
| 1 | 10 | $10.80 | Total: $108.00 |
| 1 | 5 | $12.75 | Total: $63.75 |
Data sheet
| Molecular Formula | C23H30N2O2 |
| Molecular Weight | 366.51 |
| CAS Numbers | 2095432-55-4 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | SR-18292; SR 18292; SR18292 |
| IUPAC/Chemical Name | 1-[(1,1-dimethylethyl)[(4-methylphenyl)methyl]amino]-3-(1H-indol-4-yloxy)-2-propanol |
| InChl Key | BNRANURXPKRRKP-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C23H30N2O2/c1-17-8-10-18(11-9-17)14-25(23(2,3)4)15-19(26)16-27-22-7-5-6-21-20(22)12-13-24-21/h5-13,19,24,26H,14-16H2,1-4H3 |
| SMILES Code | CC(C)(C)N(CC(O)COC1=CC=CC2=C1C=CN2)CC3=CC=C(C)C=C3 |
| References | 1) Sharabi, K., et al. Selective chemical inhibition of PGC-1α gluconeogenic activity ameliorates Type 2 Diabetes. Cell 169(1), 148-160 (2017). |
More info
Novel Selective Inhibitor of PGC-1alpha Gluconeogenic Activity, Ameliorating Type 2 Diabetes.
Reference:
Sharabi K, Lin H, Tavares CD, Dominy JE, Camporez JP, Perry RJ, Schilling R, Rines AK, Lee J, Hickey M, Bennion M, Palmer M, Nag PP, Bittker JA, Perez J, Jedrychowski MP, Ozcan U, Gygi SP, Kamenecka TM, Shulman GI, Schreiber SL, Griffin PR, Puigserver P. Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes. Cell. 2017 Mar 23;169(1):148-160.e15. doi: 10.1016/j.cell.2017.03.001. PubMed PMID: 28340340.
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