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ML299
AOB4530
CAS No: 1426916-00-8
Chemical Name: VU0463568; (S)-4-Bromo-N-(1-(1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl)propan-2-yl)benzamide
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $13.28 | Total: $1,327.50 |
| 1 | 50 | $15.34 | Total: $767.00 |
| 1 | 25 | $18.00 | Total: $449.88 |
| 1 | 10 | $21.24 | Total: $212.40 |
| 1 | 5 | $25.08 | Total: $125.38 |
Data sheet
| Molecular Formula | C23H26BeFN4O2 |
| Molecular Weight | 489.38 |
| CAS Numbers | 1426916-00-8 |
| Storage Condition | - 20C |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | ML-299; ML 299; ML299; VU0463568; VU-0463568; VU 0463568. |
| IUPAC/Chemical Name | (S)-4-bromo-N-(1-(1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl)propan-2-yl)benzamide |
| InChl Key | RFKXAYJUFUZBMA-INIZCTEOSA-N |
| InChl Code | InChI=1S/C23H26BrFN4O2/c1-16(27-21(30)17-5-7-18(24)8-6-17)14-28-11-9-23(10-12-28)22(31)26-15-29(23)20-4-2-3-19(25)13-20/h2-8,13,16H,9-12,14-15H2,1H3,(H,26,31)(H,27,30)/t16-/m0/s1 |
| SMILES Code | O=C(N[C@@H](C)CN(CC1)CCC1(N(C2=CC=CC(F)=C2)CN3)C3=O)C4=CC=C(Br)C=C4 |
| References | 1) Scott SA, et al Development of a Selective, Allosteric PLD1/2 Inhibitor in a Novel Scaffold. 2012 Apr 5 [updated 2013 Mar 14]. Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010. 2) O'Reilly MC, et al. Development of dual PLD1/2 and PLD2 selective inhibitors from a common 1,3,8-Triazaspiro[4.5]decane Core: discovery of Ml298 and Ml299 that decrease invasive migration in U87-MG glioblastoma cells. J Med Chem. 2013 Mar 28;56(6):2695-9. |
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Potent Dual PLD1/2 inhibitor
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