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MMV084978
AOB16784
CAS: 252949-96-5
Chemical Name: N'-(4-Chlorobenzoyl)-1,2,3-thiadiazole-4-carbohydrazide
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $31.05 | Total: $3,105.00 |
| 1 | 50 | $35.88 | Total: $1,794.00 |
| 1 | 25 | $42.09 | Total: $1,052.25 |
| 1 | 10 | $49.68 | Total: $496.80 |
| 1 | 5 | $58.65 | Total: $293.25 |
Data sheet
| Molecular Formula | C10H7ClN4O2S |
| Molecular Weight | 282.70 |
| CAS Numbers | 252949-96-5 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | MM-V084978, MMV-084978, MM V084978,MM-V-084978 |
| IUPAC/Chemical Name | N'-(4-Chlorobenzoyl)-1,2,3-thiadiazole-4-carbohydrazide |
| InChl Key | ISGXNGZTDDQPFG-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C10H7ClN4O2S/c11-7-3-1-6(2-4-7)9(16)13-14-10(17)8-5-18-15-12-8/h1-5H,(H,13,16)(H,14,17) |
| SMILES Code | O=C(C1=CSN=N1)NNC(C2=CC=C(Cl)C=C2)=O |
| References | 1) Summers RL, et al., Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention. Cell Chem Biol. 2022 Feb 17;29(2):191-201.e8. doi: 10.1016/j.chembiol.2021.07.010. Epub 2021 Aug 3. PMID: 34348113 |
| PubChem ID | PMC8878317 |
More info
Novel specific inhibitor of PfAcAS by competing with substrates, directly inhibiting the enzyme by preventing CoA and acetate binding