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PXS-5505 dihydrochloride
AOB16988
CAS: 2409964-23-2 (free base: 2409963-83-1)
Chemical Name: LOX-IN-3; (Z)-3-Fluoro-4-quinolin-8-ylsulfonylbut-2-en-1-amine Dihydrochloride
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $12.15 | Total: $1,215.00 |
| 1 | 50 | $14.04 | Total: $702.00 |
| 1 | 25 | $16.47 | Total: $411.75 |
| 1 | 10 | $19.44 | Total: $194.40 |
| 1 | 5 | $22.95 | Total: $114.75 |
Data sheet
| Molecular Formula | C13H15Cl2FN2O2S |
| Molecular Weight | 353.2 |
| CAS Numbers | 2409964-23-2 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO and Water |
| Purity | 98% by HPLC |
| Synonym | LOX-IN-3 dihydrochloride; PXS5505 |
| IUPAC/Chemical Name | (Z)-3-fluoro-4-quinolin-8-ylsulfonylbut-2-en-1-amine dihydrochloride |
| InChl Key | YYYHSAUHJBNINZ-LEOXJOGCSA-N |
| InChl Code | InChI=1S/C13H13FN2O2S.2ClH/c14-11(6-7-15)9-19(17,18)12-5-1-3-10-4-2-8-16-13(10)12;;/h1-6,8H,7,9,15H2;2*1H/b11-6- |
| SMILES Code | C1=CC2=C(C(=C1)S(=O)(=O)CC(=CCN)F)N=CC=C2.Cl.Cl |
| References | 1) Yao, Y., et al.,Pan-Lysyl Oxidase Inhibitor PXS-5505 Ameliorates Multiple-Organ Fibrosis by Inhibiting Collagen Crosslinks in Rodent Models of Systemic Sclerosis; Int. J. Mol. Sci. 2022, 23(10), 5533; https://doi.org/10.3390/ijms23105533 |
More info
Novel orally available, small-molecule, irreversible inhibitor of all lysyl oxidases (LOX) family members