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ASM inhibitor 4i
AOB15890
CAS: 2913151-46-7
Chemical Name: 3-(4-((4-Bromophenoxy)methyl)phenyl)-N-hydroxy-1,2,4-oxadiazole-5-carboxamide
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $35.55 | Total: $3,555.00 |
| 1 | 50 | $41.08 | Total: $2,054.00 |
| 1 | 25 | $48.19 | Total: $1,204.75 |
| 1 | 10 | $56.88 | Total: $568.80 |
| 1 | 5 | $67.15 | Total: $335.75 |
Data sheet
| Molecular Formula | C16H12BrN3O4 |
| Molecular Weight | 390.19 |
| CAS Numbers | 2913151-46-7 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 3-(4-((4-Bromophenoxy)methyl)phenyl)-N-hydroxy-1,2,4-oxadiazole-5-carboxamide |
| SMILES Code | BrC1=CC=C(OCC2=CC=C(C3=NOC(C(NO)=O)=N3)C=C2)C=C1 |
| References | 1) Yang K, et al. Discovery of Novel N-Hydroxy-1,2,4-oxadiazole-5-formamides as ASM Direct Inhibitors for the Treatment of Atherosclerosis. J Med Chem. 2023 Feb 23;66(4):2681-2698. |
More info
Novel direct inhibitor of acid sphingomyelinase (ASM), significantly decreasing LPS-induced and Ox-LDL-induced cell inflammation by regulating the levels of ceramide and sphingomyelin