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View larger Sodium etidronate
AT1210
CAS 7414-83-7
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Data sheet
| Molecular Formula | C2H6Na2O7P2 |
| Molecular Weight | 249.99 |
| CAS Numbers | 7414-83-7 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | |
| IUPAC/Chemical Name | |
| InChl Key | |
| InChl Code | |
| SMILES Code | [Na+].[Na+].CC(O)(P(O)([O-])=O)P(O)([O-])=O |
| References | Grases F, et al. Circ J. 2007 Jul; 71[7] 1152-6. |
More info
Sodium etidronate (Didronel) is a synthetic therapeutic diphosphonate analog of endogenous pyrophosphate. As a member of the family of drugs known as bisphosphonates, Sodium etidronate differs from endogenous pyrophosphate in its resistance to enzymatic hydrolysis. This agent adsorbs to hydroxyapatite cells and reduces the number of osteoclasts, thereby inhibiting abnormal bone resorption. Etidronate may also directly stimulate bone formation by osteoblasts.