Enzyme Inhibitors

Sodium etidronate View larger

Sodium etidronate

AT1210

CAS 7414-83-7

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$36.00

$36.00 per 500 mg

Data sheet

Molecular FormulaC2H6Na2O7P2
Molecular Weight249.99
CAS Numbers7414-83-7
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
Synonym
IUPAC/Chemical Name
InChl Key
InChl Code
SMILES Code[Na+].[Na+].CC(O)(P(O)([O-])=O)P(O)([O-])=O
ReferencesGrases F, et al. Circ J. 2007 Jul; 71[7] 1152-6.

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Sodium etidronate (Didronel) is a synthetic therapeutic diphosphonate analog of endogenous pyrophosphate. As a member of the family of drugs known as bisphosphonates, Sodium etidronate differs from endogenous pyrophosphate in its resistance to enzymatic hydrolysis. This agent adsorbs to hydroxyapatite cells and reduces the number of osteoclasts, thereby inhibiting abnormal bone resorption. Etidronate may also directly stimulate bone formation by osteoblasts.