Enzyme Inhibitors

BCI View larger

BCI

AT10486

CAS 1245792-51-1

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$44.00

$44.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $19.80 Total: $1,980.00
150 $22.88 Total: $1,144.00
125 $26.84 Total: $671.00
110 $31.68 Total: $316.80
15 $37.40 Total: $187.00

Data sheet

Molecular FormulaC22H23NO
Molecular Weight317.42
CAS Numbers1245792-51-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C1C(=Cc2ccccc2)C(NC2CCCCC2)c2ccccc12
ReferencesKorotchenko VN, et al. In vivo structure-activity relationship studies support allosteric targeting of a dual specificity phosphatase. Chembiochem. 2014 Jul 7;15[10] 1436-45.

More info

BCI ((E)-BCI) is an allosteric inhibitor of dual-specificity phosphatases (DUSP), with EC50 values of 13.3 ?M for DUSP6 and 8.0 ?M for DUSP1 in cells, and does not inhibit DUSP5.