Enzyme Inhibitors

Navitoclax-piperazine View larger

Navitoclax-piperazine

AT12186

CAS 2143096-93-7

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HOW TO ORDER

$134.00

$134.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $60.30 Total: $6,030.00
150 $69.68 Total: $3,484.00
125 $81.74 Total: $2,043.50
110 $96.48 Total: $964.80
15 $113.90 Total: $569.50

Data sheet

Molecular FormulaC47H56ClF3N6O5S3
Molecular Weight973.63
CAS Numbers2143096-93-7
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC1(C)CCC(=C(CN2CCN(CC2)c2ccc(cc2)C(=O)NS(=O)(=O)c2ccc(N[C@H](CCN3CCNCC3)CSc3ccccc3)c(c2)S(=O)(=O)C(F)(F)F)C1)c1ccc(Cl)cc1
ReferencesSajid Khan, et al. A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity. Nat Med 25, 1938

More info

Navitoclax-piperazine (ABT-263-piperazine) is a B-cell lymphoma extra large (BCL-XL) inhibitor.