Enzyme Inhibitors

Vorasidenib View larger

Vorasidenib

AT7307

CAS 1644545-52-7

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$41.00

$41.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $18.45 Total: $1,845.00
150 $21.32 Total: $1,066.00
125 $25.01 Total: $625.25
110 $29.52 Total: $295.20
15 $34.85 Total: $174.25

Data sheet

Molecular FormulaC14H13ClF6N6
Molecular Weight414.74
CAS Numbers1644545-52-7
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC[C@@H](Nc1nc(N[C@H](C)C(F)(F)F)nc(n1)-c1cccc(Cl)n1)C(F)(F)F
ReferencesZakkula A, Dittakavi S, Maniyar MM,et al.Validated HPLC method for simultaneous quantification of mutant IDH12 inhibitors [enasidenib, ivosidenib and vorasidenib] in mouse plasma Application to a pharmacokinetic study[J].Biomed Chromatogr. 2019 Nov;33[11] e4658.

More info

Vorasidenib (PVMMA) is an inhibitor of mutant isocitrate dehydrogenase (IDH; IC50s = 31.9 and 31.7 nM for IDH1R132H and IDH2R140Q, respectively)