Enzyme Inhibitors

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Aristolactam I

AT3S1227

CAS 13395-02-3

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$47.00

$47.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $21.15 Total: $2,115.00
150 $24.44 Total: $1,222.00
125 $28.67 Total: $716.75
110 $33.84 Total: $338.40
15 $39.95 Total: $199.75

Data sheet

Molecular FormulaC17H11NO4
Molecular Weight293.27
CAS Numbers13395-02-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCOc1cccc2c1cc1NC(=O)c3cc4OCOc4c2c13
ReferencesLi J , Zhang L , Jiang Z , et al. Toxicities of aristolochic acid I and aristololactam I in cultured renal epithelial cells[J]. Toxicology in Vitro, 2010, 24[4] 0-1097.

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1.Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway. 2. The effects of Aristololactam I may be mediated by different mechanisms except TGF-beta1 pathway. 3. Aristololactam I may be one of toxic metabolites in Chinese herbs containing AA which participate in renal damage and fibrosis.