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Enzyme Inhibitors

BMT-124110 Formate View larger

BMT-124110 Formate

AT10572L

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$166.00

$166.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $141.10 Total: $705.50
110 $119.52 Total: $1,195.20
125 $101.26 Total: $2,531.50
150 $86.32 Total: $4,316.00
1100 $74.70 Total: $7,470.00

Data sheet

Molecular FormulaC22H20N2O2
Molecular Weight344.41
CAS Numbers1431525-23-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C(C1=CC=CC=C1)NC2=CC=CC(C(NC3=C(CC)C=CC=C3)=O)=C2.[H]C(O)=O
ReferencesKostich W, et al. Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain. J Pharmacol Exp Ther. 2016;358[3] 371-386.

More info

BMT-124110 Formate is a selective AAK1 inhibitor (IC50: 0.9 nM) with anti-injury sensory activity.BMT-124110 Formate inhibits the BMP-2-inducible protein kinase BIKE with an IC50: 17 nM.BMT-124110 Formate inhibits the cell-cycle protein G-related BMT-124110 Formate inhibits the cell cycle protein G-associated kinase GAK with an IC50:99 nM.