Enzyme Inhibitors

CRT-0105950 View larger

CRT-0105950

AT23917

CAS 1661845-86-8

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$50.00

$50.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $22.50 Total: $2,250.00
150 $26.00 Total: $1,300.00
125 $30.50 Total: $762.50
110 $36.00 Total: $360.00
15 $42.50 Total: $212.50

Data sheet

Molecular FormulaC21H16ClN3OS
Molecular Weight393.89
CAS Numbers1661845-86-8
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCc1ccc(c(Cl)c1)-c1cnccc1-c1cnc(Nc2ccc(O)cc2)s1
ReferencesMardilovich K, et al. LIM kinase inhibitors disrupt mitotic microtubule organization and impair tumor cell proliferation. Oncotarget. 2015 Nov 17;6[36] 38469-86.

More info

CRT-0105950 is a potent LIMK inhibitor with high affinity for both LIMK1 and LIMK2.CRT-0105950 inhibits filamentous cutin phosphorylation and promotes ?-microtubulin acetylation in cells.CRT-0105950 can be used in the study of renal carcinoma.