Enzyme Inhibitors

FL118 View larger

FL118

AT77701

CAS 135415-73-5

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$68.00

$68.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $30.60 Total: $3,060.00
150 $35.36 Total: $1,768.00
125 $41.48 Total: $1,037.00
110 $48.96 Total: $489.60
15 $57.80 Total: $289.00

Data sheet

Molecular FormulaC21H16N2O6
Molecular Weight392.36
CAS Numbers135415-73-5
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC(C)[C@]1(O)C2=C(C(=O)N3C(=C2)C=4C(C3)=CC=5C(N4)=CC6=C(C5)OCO6)COC1=O
ReferencesZhao H, et al. FL118, a novel anticancer compound, inhibits proliferation and migration of ovarian cancer cells via up-regulation of cytoglobin in vivo and in vitro[J]. Translational Cancer Research, 2017, 6[6] 1294-1304.

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FL118 is a novel survivin inhibitor that inhibits cancer stem cell-like properties.FL118 is a novel camptothecin analog with anticancer activity that inhibits epithelial-mesenchymal transition through the Wnt?-catenin signaling pathway, thereby inhibiting migration and invasion of human breast cancer cells.