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View larger Safingol hydrochloride
AT83978
CAS 139755-79-6
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $74.70 | Total: $7,470.00 |
| 1 | 50 | $86.32 | Total: $4,316.00 |
| 1 | 25 | $101.26 | Total: $2,531.50 |
| 1 | 10 | $119.52 | Total: $1,195.20 |
| 1 | 5 | $141.10 | Total: $705.50 |
Data sheet
| Molecular Formula | C18H40ClNO2 |
| Molecular Weight | 337.969 |
| CAS Numbers | 139755-79-6 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(CCCCCCCCCCCCCC)[C@@H]([C@H](CO)N)O.Cl |
| References | Tan KB,et al. In vivo efficacy of a novel liposomal formulation of safingol in the treatment of acute myeloid leukemia. J Control Release. 2012 Jun 10;160[2] 290-8. |
More info
Safingol hydrochloride (L-threo-dihydrosphingosine hydrochloride) is a specific inhibitor of protein kinase C. It induces autophagy in solid tumor cells and cancer cell death by inhibiting the PKC and PI3-kinase pathways.BIIB 722 Mesylate is a selective sodium-hydrogen exchange inhibitor. Safingol hydrochloride inhibits PKC and PI3k.