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Enzyme Inhibitors
- Protein Control Ligand
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View larger TCS 21311
AT17019
CAS 1260181-14-3
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $71.40 | Total: $357.00 |
| 1 | 10 | $60.48 | Total: $604.80 |
| 1 | 25 | $51.24 | Total: $1,281.00 |
| 1 | 50 | $43.68 | Total: $2,184.00 |
| 1 | 100 | $37.80 | Total: $3,780.00 |
Data sheet
| Molecular Formula | C27H25F3N4O4 |
| Molecular Weight | 526.51 |
| CAS Numbers | 1260181-14-3 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(C)(O)C(=O)N1CCN(CC1)c1ccc(c(c1)C1=C(C(=O)NC1=O)c1c[nH]c2ccccc12)C(F)(F)F |
More info
TCS 21311 (NIBR3049) is an effective and highly selective inhibitor of JAK3 (IC50: 8 nM). TCS 21311 inhibits PKC?, PKC?, and GSK3? (IC50s: 13, 68, and 3 nM, respectively). It displays >100-fold selectivity over JAK1, JAK2, and TYK2.