Enzyme Inhibitors

SMI-16a View larger

SMI-16a

AT3989

CAS 587852-28-6

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$26.00

$26.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $11.70 Total: $1,170.00
150 $13.52 Total: $676.00
125 $15.86 Total: $396.50
110 $18.72 Total: $187.20
15 $22.10 Total: $110.50

Data sheet

Molecular FormulaC13H13NO3S
Molecular Weight263.31
CAS Numbers587852-28-6
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCCCOc1ccc(C=C2SC(=O)NC2=O)cc1
ReferencesXia Z., et al. Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases. J Med Chem. 2009 Jan 8;52[1] 74-86.

More info

SMI-16a (PIM12 Kinase Inhibitor VI) , a cell-permeable thiazolidinedione compound, acts as an effective, ATP-competitive inhibitor against Pim-12 kinases (IC50: 15020 nM) while exhibiting little or no activity against a panel of 57 other kinases (?18% inhibition at 5 ?M).