Enzyme Inhibitors

QS11 View larger

QS11

AT4022

CAS 944328-88-5

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$31.00

$31.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $13.95 Total: $1,395.00
150 $16.12 Total: $806.00
125 $18.91 Total: $472.75
110 $22.32 Total: $223.20
15 $26.35 Total: $131.75

Data sheet

Molecular FormulaC36H33N5O2
Molecular Weight567.68
CAS Numbers944328-88-5
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeOC[C@H](Cc1ccccc1)Nc1nc(Oc2ccc3CCCc3c2)nc2n(Cc3ccc(cc3)-c3ccccc3)cnc12
ReferencesEmre N., et al. A chemical approach to stem cell biology. Curr Opin Chem Biol. 2007 Jun;11[3] 252-8.

More info

QS11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt?-catenin signaling pathway to upregulate ?-catenin nuclear translocation. Also reduces in vitro migration of metastatic human breast cancer cells.