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Enzyme Inhibitors

Setrobuvir View larger

Setrobuvir

AT28762

CAS 1071517-39-9

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$204.00

$204.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $173.40 Total: $867.00
110 $146.88 Total: $1,468.80
125 $124.44 Total: $3,111.00
150 $106.08 Total: $5,304.00
1100 $91.80 Total: $9,180.00

Data sheet

Molecular FormulaC25H25FN4O6S2
Molecular Weight560.62
CAS Numbers1071517-39-9
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC(N1[C@@]2([C@@]([C@@]3(C[C@]2(CC3)[H])[H])(C(O)=C(C1=O)C=4NC=5C(S(=O)(=O)N4)=CC(NS(C)(=O)=O)=CC5)[H])[H])C6=CC=C(F)C=C6
ReferencesYi G, et al. Biochemical study of the comparative inhibition of hepatitis C virus RNA polymerase by VX-222 and filibuvir. Antimicrob Agents Chemother. 2012 ; 56[2] 830-837.

More info

Setrobuvir (ANA-598) is an orally active non-nucleoside HCV NS5B polymerase inhibitor with inhibitory effects on de novo RNA synthesis and primer extension with IC50s between 4 and 5 nM. setrobuvir shows good binding affinity for SARS-CoV-2 RdRp and induces inhibition of RdRp.