Enzyme Inhibitors

Ro 90-7501 View larger

Ro 90-7501

AT16773

CAS 293762-45-5

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$26.00

$26.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $11.70 Total: $1,170.00
150 $13.52 Total: $676.00
125 $15.86 Total: $396.50
110 $18.72 Total: $187.20
15 $22.10 Total: $110.50

Data sheet

Molecular FormulaC20H16N6
Molecular Weight340.38
CAS Numbers293762-45-5
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeNC1=CC=C(C=C1)C1=NC2=C(N1)C=C(C=C2)C1=NC2=C(N1)C=C(N)C=C2
ReferencesGuo F, et al. RO 90-7501 enhances TLR3 and RLR agonist induced antiviral response. PLoS One. 2012;7[10] e42583.

More info

Ro 90-7501 is an amyloid ?42 (A?42) protofibrillar and TPR-dependent PP5 inhibitor, a novel radiosensitizer for cervical cancer cells, which inhibits ATM phosphorylation, promotes apoptosis, and induces cell-cycle arrest. Ro 90-7501 also exhibits antiviral activity and potential anticancer activity by inhibiting ATM phosphorylation and DNA repair, and by inhibiting HCMV.