Enzyme Inhibitors

Sisunatovir hydrochloride View larger

Sisunatovir hydrochloride

AT9197

CAS 1903763-83-6

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$47.00

$47.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $21.15 Total: $2,115.00
150 $24.44 Total: $1,222.00
125 $28.67 Total: $716.75
110 $33.84 Total: $338.40
15 $39.95 Total: $199.75

Data sheet

Molecular FormulaC23H23ClF4N4O
Molecular Weight482.9
CAS Numbers1903763-83-6
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCl.NCc1ccc2n(CCCC(F)(F)F)c(CN3C(=O)C4(CC4)c4ccc(F)cc34)nc2c1
ReferencesCockerill G S , Angell R M , Bedernjak A , et al. Discovery of Sisunatovir [RV521], an Inhibitor of Respiratory Syncytial Virus Fusion[J]. Journal of medicinal chemistry, 64[7] 3658-3676.

More info

Sisunatovir hydrochloride (RV521 HCl) is an orally available inhibitor of the RSV-F protein that has exhibited potent efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses in vitro (IC50 = 1.4 nM for RSV-A, IC50 = 1.0 nM for RSV-B).