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Enzyme Inhibitors
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View larger Siguazodan
AT12913
CAS 115344-47-3
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $97.75 | Total: $488.75 |
| 1 | 10 | $82.80 | Total: $828.00 |
| 1 | 25 | $70.15 | Total: $1,753.75 |
| 1 | 50 | $59.80 | Total: $2,990.00 |
| 1 | 100 | $51.75 | Total: $5,175.00 |
Data sheet
| Molecular Formula | C14H16N6O |
| Molecular Weight | 284.32 |
| CAS Numbers | 115344-47-3 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CNC(NC#N)=Nc1ccc(cc1)C1=NNC(=O)CC1C |
| References | Murray KJ, et al. The effects of siguazodan, a selective phosphodiesterase inhibitor, on human platelet function. Br J Pharmacol. 1990 Mar;99[3] 612-6. |
More info
Siguazodan (SKF 94836) is an effective, selective, orally active phosphodiesterase III ((PDE-III)) inhibitor with an IC50 of 117 nM. Siguazodan inhibited phenylephrine induced 5-HT release with an IC50 value of 4.2 ?M? Siguazodan can increase cAMP accumulation in intact platelets, with EC50 of 18.88 ?M?