Enzyme Inhibitors

SAG View larger

SAG

AT1779

CAS 912545-86-9

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$40.00

$40.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $18.00 Total: $1,800.00
150 $20.80 Total: $1,040.00
125 $24.40 Total: $610.00
110 $28.80 Total: $288.00
15 $34.00 Total: $170.00

Data sheet

Molecular FormulaC28H28ClN3OS
Molecular Weight490.06
CAS Numbers912545-86-9
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCN[C@H]1CC[C@@H](CC1)N(Cc1cccc(c1)-c1ccncc1)C(=O)c1sc2ccccc2c1Cl
ReferencesXu H, et al. Directed Differentiation of V3 Interneurons from Mouse Embryonic Stem Cells. Stem Cells Dev. 2015 Nov 15;24[22] 2723-32.

More info

SAG (Smoothened Agonist) is a Smo receptor agonist (EC50=3 nM) that is cell-permeable and selective. SAG regulates Smo activity by binding directly to the Smo helix and can activate the Hedgehog signaling pathway.