Enzyme Inhibitors

VH032 View larger

VH032

AT29106

CAS 1448188-62-2

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$37.00

$37.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $16.65 Total: $1,665.00
150 $19.24 Total: $962.00
125 $22.57 Total: $564.25
110 $26.64 Total: $266.40
15 $31.45 Total: $157.25

Data sheet

Molecular FormulaC24H32N4O4S
Molecular Weight472.6
CAS Numbers1448188-62-2
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)C(C)(C)C
ReferencesChan KH, et al. Impact of target warhead and linkage vector on inducing protein degradation comparison of Bromodomain and Extra-Terminal [BET] degraders derived from triazolodiazepine [JQ1] and tetrahydroquinoline [I-BET726] BET inhibitor scaffolds. J Med Chem. 2017 Jun 8.

More info

VH032 commonly used as a precursor to a PROTAC that hijacks VHL as the E3 ubiquitin ligase component.VH032 is a VHLHIF-1? interaction inhibitor with a KdPROTACs, which can recruit von Hippel-Lindau (VHL) proteins as a ligand of VHL.