Enzyme Inhibitors

YHO-13351 View larger

YHO-13351

AT13366

CAS 1346753-00-1

More details

Molarity Calculation Cart®

HOW TO ORDER

$26.00

$26.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $11.70 Total: $1,170.00
150 $13.52 Total: $676.00
125 $15.86 Total: $396.50
110 $18.72 Total: $187.20
15 $22.10 Total: $110.50

Data sheet

Molecular FormulaC27H37N3O7S2
Molecular Weight579.73
CAS Numbers1346753-00-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeS(C)(=O)(=O)O.C(=C(C#N)C1=CC(OC)=C(OC)C=C1)C=2SC(=CC2)N3CCC(OC(CN(CC)CC)=O)CC3
ReferencesYamazaki R, et al. Novel acrylonitrile derivatives, YHO-13177 and YHO-13351, reverse BCRPABCG2-mediated drug resistance in vitro and in vivo. Mol Cancer Ther. 2011 Jul;10[7] 1252-63.

More info

YHO-13351 is an ABCG2 inhibitor, an acrylonitrile derivative, that induces sensitization of cancer steminitiating-like side population cells to irinotecan.GSK1702934A can be used to study diabetes.