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View larger Z-VAD(OMe)-FMK
AT6013
CAS 187389-52-2
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $37.40 | Total: $187.00 |
| 1 | 10 | $31.68 | Total: $316.80 |
| 1 | 25 | $26.84 | Total: $671.00 |
| 1 | 50 | $22.88 | Total: $1,144.00 |
| 1 | 100 | $19.80 | Total: $1,980.00 |
Data sheet
| Molecular Formula | C22H30FN3O7 |
| Molecular Weight | 467.49 |
| CAS Numbers | 187389-52-2 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COC(=O)C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(=O)CF |
| References | Shimizu T, et al. Camptothecin-induced apoptosis in p53-null human leukemia HL60 cells and their isolated nuclei effects of the protease inhibitors Z-VAD-fmk and dichloroisocoumarin suggest an involvement of both caspases and serine proteases. Leukemia. 1997 Aug;11[8] 1238-44. |
More info
Z-VAD(OMe)-FMK is a pan-caspase inhibitor with irreversible properties; Z-VAD(OMe)-FMK is also an inhibitor of ubiquitin C terminal hydrolase L1 (UCHL1), which is irreversibly modified by targeting the UCHL1 active site.