Enzyme Inhibitors

ALK2-IN-2 View larger

ALK2-IN-2

AT10287

CAS 2254409-25-9

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$79.00

$79.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $35.55 Total: $3,555.00
150 $41.08 Total: $2,054.00
125 $48.19 Total: $1,204.75
110 $56.88 Total: $568.80
15 $67.15 Total: $335.75

Data sheet

Molecular FormulaC28H27N5O2S
Molecular Weight497.61
CAS Numbers2254409-25-9
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(N1CCCC1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccc(c2ccccc12)S(N)(=O)=O
ReferencesJiang JK, et al. Discovery of 3-[4-sulfamoylnaphthyl]pyrazolo[1,5-a]pyrimidines as potent and selective ALK2 inhibitors. Bioorg Med Chem Lett. 2018 ; 28[20] 3356-3362.

More info

ALK2-IN-2 is a potent and selective inhibitor of activin receptor-like kinase 2 (ALK2) with an IC50 of 9 nM, demonstrating 700-fold higher inhibition of ALK2 compared to ALK3.