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View larger TAS4464 hydrochloride
AT13090
CAS 1848959-11-4
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HOW TO ORDER
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $23.40 | Total: $2,340.00 |
| 1 | 50 | $27.04 | Total: $1,352.00 |
| 1 | 25 | $31.72 | Total: $793.00 |
| 1 | 10 | $37.44 | Total: $374.40 |
| 1 | 5 | $44.20 | Total: $221.00 |
Data sheet
| Molecular Formula | C21H24ClFN6O6S |
| Molecular Weight | 542.97 |
| CAS Numbers | 1848959-11-4 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.CCOc1cccc(F)c1C#Cc1cn([C@@H]2O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]2O)c2ncnc(N)c12 |
| References | Yoshimura C, et al. TAS4464, a highly potent and selective inhibitor of NEDD8 activating enzyme, suppresses neddylation and shows antitumor activity in diverse cancer models. Mol Cancer Ther. 2019 May 15. |
More info
TAS4464 hydrochloride is a highly potent and selective NEDD8 activating enzyme (NAE) inhibitor(IC50 of 0.955 nM).