Enzyme Inhibitors

Y06137 View larger

Y06137

AT13363

CAS 2226534-49-0

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$47.00

$47.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $21.15 Total: $2,115.00
150 $24.44 Total: $1,222.00
125 $28.67 Total: $716.75
110 $33.84 Total: $338.40
15 $39.95 Total: $199.75

Data sheet

Molecular FormulaC27H32N4O2
Molecular Weight444.57
CAS Numbers2226534-49-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC[C@H]1COCCN1c1ccc2nc(-c3ccc4onc(C)c4c3)n(CC3CCCCC3)c2c1
ReferencesZhang M, et al. Structure-Based Discovery and Optimization of Benzo[ d]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer [CRPC]. J Med Chem. 2018 Apr 12;61[7] 3037-3058.

More info

Y06137 is an effective and selective BET inhibitor with a Kd of 81 nM for BRD4(1) bromodomain. Y06137 can be used for research on the treatment of castration-resistant prostate cancer.