Enzyme Inhibitors

YHO-13351 free base View larger

YHO-13351 free base

AT13365

CAS 912288-64-3

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$26.00

$26.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $11.70 Total: $1,170.00
150 $13.52 Total: $676.00
125 $15.86 Total: $396.50
110 $18.72 Total: $187.20
15 $22.10 Total: $110.50

Data sheet

Molecular FormulaC26H33N3O4S
Molecular Weight483.62
CAS Numbers912288-64-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCCN(CC)CC(=O)OC1CCN(CC1)c1ccc(C=C(C#N)c2ccc(OC)c(OC)c2)s1
ReferencesYamazaki R, et al. Novel acrylonitrile derivatives, YHO-13177 and YHO-13351, reverse BCRPABCG2-mediated drug resistance in vitro and in vivo. Mol Cancer Ther. 2011 Jul;10[7] 1252-63.

More info

YHO-13351 free base, the water-soluble prodrug of YHO-13177, is an inhibitor of BCRP (breast cancer resistance protein).