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View larger Rhosin hydrochloride
AT16745
CAS 1281870-42-5
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $117.30 | Total: $586.50 |
| 1 | 10 | $99.36 | Total: $993.60 |
| 1 | 25 | $84.18 | Total: $2,104.50 |
| 1 | 50 | $71.76 | Total: $3,588.00 |
| 1 | 100 | $62.10 | Total: $6,210.00 |
Data sheet
| Molecular Formula | C20H20Cl2N6O |
| Molecular Weight | 431.318 |
| CAS Numbers | 1281870-42-5 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.N[C@H](Cc1c[nH]c2ccccc12)C(=O)NN=Cc1ccc2nccnc2c1 |
| References | Shang X, et al. Rational design of small molecule inhibitors targeting RhoA subfamily Rho GTPases. Chem Biol. 2012 Jun 22;19[6] 699-710. |
More info
Rhosin hydrochloride is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM). Rhosin hydrochloride does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin hydrochloride causes cell apoptosis.