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Enzyme Inhibitors
- Protein Control Ligand
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- Protease
- Synthase
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View larger BMS-986176
AT35856
CAS 1815613-42-3
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $126.65 | Total: $633.25 |
| 1 | 10 | $107.28 | Total: $1,072.80 |
| 1 | 25 | $90.89 | Total: $2,272.25 |
| 1 | 50 | $77.48 | Total: $3,874.00 |
| 1 | 100 | $67.05 | Total: $6,705.00 |
Data sheet
| Molecular Formula | C19H23F4N3O |
| Molecular Weight | 385.4 |
| CAS Numbers | 1815613-42-3 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(C)C[C@](C)(N)COc1ccc(nc1C(F)F)-c1ccnc(c1)C(F)F |
| References | Guanglin Luo, et al. Discovery of [ S]-1-[[2',6-Bis[difluoromethyl]-[2,4'-bipyridin]-5-yl]oxy]-2,4-dimethylpentan-2-amine [BMS-986176LX-9211] A Highly Selective, CNS Penetrable, and Orally Active Adaptor Protein-2 Associated Kinase 1 Inhibitor in Clinical Trials for the Treatment of Neuropathic Pain. J Med Chem. 2022 Mar 24;65[6] 4457-4480. |
More info
AAK1-IN-1 is a highly selective and potent inhibitor of adaptor associated kinase 1 (AAK1, IC50 = 2 nM).