Enzyme Inhibitors

NVP-BHG712 View larger

NVP-BHG712

AT6348

CAS 940310-85-0

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$26.00

$26.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $11.70 Total: $1,170.00
150 $13.52 Total: $676.00
125 $15.86 Total: $396.50
110 $18.72 Total: $187.20
15 $22.10 Total: $110.50

Data sheet

Molecular FormulaC26H20F3N7O
Molecular Weight503.48
CAS Numbers940310-85-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCc1ccc(cc1Nc1nc(nc2n(C)ncc12)-c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F
ReferencesMartiny-Baron G, et al. Angiogenesis. 2010, 13[3], 259-267.

More info

NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 ?M, 1.266 ?M and 1.667 ?M, respectively.