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View larger TGF?RI-IN-3
AT9523
CAS 2763602-67-9
1000 Items
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $57.80 | Total: $289.00 |
| 1 | 10 | $48.96 | Total: $489.60 |
| 1 | 25 | $41.48 | Total: $1,037.00 |
| 1 | 50 | $35.36 | Total: $1,768.00 |
| 1 | 100 | $30.60 | Total: $3,060.00 |
Data sheet
| Molecular Formula | C28H23N3O2S |
| Molecular Weight | 465.57 |
| CAS Numbers | 2763602-67-9 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N(C=1C2=C(C=C(C=C2)C3=CC=C(S(C)(=O)=O)C=C3)N=CC1)C=4C=C(N=CC4)C5=CC(C)=CC=C5 |
| References | Kharbanda A, et al. Discovery of 4-aminoquinolines as highly selective TGF?R1 inhibitors with an attenuated MAP4K4 profile for potential applications in immuno-oncology [published online ahead of print, 2021 Aug 12]. Eur J Med Chem. 2021;225 113763. |
More info
TGF?RI-IN-3 is a highly selective TGF?R1 inhibitor with an IC50 of 0.79 nM and exhibits 2000-fold selectivity against MAP4K4, showing potential applications in immuno-oncology [1].