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View larger AWL-II-38.3
AT38511
CAS 1135205-94-5
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $53.55 | Total: $267.75 |
| 1 | 10 | $45.36 | Total: $453.60 |
| 1 | 25 | $38.43 | Total: $960.75 |
| 1 | 50 | $32.76 | Total: $1,638.00 |
| 1 | 100 | $28.35 | Total: $2,835.00 |
Data sheet
| Molecular Formula | C23H18F3N5O3 |
| Molecular Weight | 469.42 |
| CAS Numbers | 1135205-94-5 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cc1cn(cn1)-c1cc(cc(c1)C(F)(F)F)C(=O)Nc1ccc(C)c(NC(=O)c2ccno2)c1 |
| References | Yongmun Choi, et al. Discovery and structural analysis of Eph receptor tyrosine kinase inhibitors. Bioorg Med Chem Lett. 2009 Aug 1;19[15] 4467-70. |
More info
AWL-II-38.3 is a highly effective inhibitor of EphA3, a receptor for ephrin-A. It demonstrates potent kinase inhibitory activity against EphA3 and does not show significant cellular activity against Src-family kinases or b-raf [1] [2].