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DG172 dihydrochloride
AOB5825
CAS No: 1361504-77-9
Chemical Name: DG172 dihydrochloride; 2-(2-Bromo-phenyl)-3-[4-(4-methyl-piperazin-1-yl)-phenyl]-acrylonitrile dihydrochloride
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $6.75 | Total: $675.00 |
| 1 | 50 | $7.80 | Total: $390.00 |
| 1 | 25 | $9.15 | Total: $228.75 |
| 1 | 10 | $10.80 | Total: $108.00 |
| 1 | 5 | $12.75 | Total: $63.75 |
Data sheet
| Molecular Formula | C20H22BrCl2N3 |
| Molecular Weight | 455.22 |
| CAS Numbers | 1361504-77-9 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 2-bromo-αZ-[[4-(4-methyl-1-piperazinyl)phenyl]methylene]-benzeneacetonitrile, dihydrochloride |
| InChl Key | SABUORLIDVBCPI-WTLOABTRSA-N |
| InChl Code | InChI=1S/C20H20BrN3.2ClH/c1-23-10-12-24(13-11-23)18-8-6-16(7-9-18)14-17(15-22)19-4-2-3-5-20(19)21;;/h2-9,14H,10-13H2,1H3;2*1H/b17-14+;; |
| SMILES Code | CN1CCN(C2=CC=C(/C=C(C#N)/C3=C(Br)C=CC=C3)C=C2)CC1.Cl.Cl |
| References | 1) Lieber, S., Scheer, F., Meissner, W., et al. (Z)-2-(2-bromophenyl)-3-{[4-(1-methyl-piperazine)amino]phenyl}acrylonitrile (DG172): An orally bioavailable PPARβ/δ-selective ligand with inverse agonistic properties. J. Med. Chem. 55(6), 2858-2868 (2012). |
More info
Orally available potent PPARß/d inverse agonist, inhibiting Angptl4 gene expression and augmenting GM-CSF/IL-4-induced differentiation of mature dendritic cells from bone marrow cells in culture