Epigenetics

CRA-026440 hydrochloride View larger

CRA-026440 hydrochloride

AT10883L

CAS 847459-98-7

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$124.00

$124.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $55.80 Total: $5,580.00
150 $64.48 Total: $3,224.00
125 $75.64 Total: $1,891.00
110 $89.28 Total: $892.80
15 $105.40 Total: $527.00

Data sheet

Molecular FormulaC23H25ClN4O4
Molecular Weight456.92
CAS Numbers847459-98-7
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCl.CN(C)CCOc1ccc2[nH]c(cc2c1)C(=O)NCC#Cc1ccc(cc1)C(=O)NO
ReferencesCao ZA, et al. CRA-026440 a potent, broad-spectrum, hydroxamic histone deacetylase inhibitor with antiproliferative and antiangiogenic activity in vitro and in vivo. Mol Cancer Ther. 2006 Jul;5[7] 1693-701.

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CRA-026440 hydrochloride is a potent and broad-spectrum HDAC inhibitor. CRA-026440 hydrochloride exhibits Ki values against recombinant HDAC isoenzymes HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC10 are 4 nM, 14 nM, 11 nM, 15 nM, 7 nM, and 20 nM, respectively. CRA-026440 hydrochloride exhibits antitumor and antiangiogenic activities.